Angioedema

Angioedema is characterized by sudden, asymmetrical, soft edema involving the deep dermis, subcutaneous tissue, or submucosa, usually without pruritus. The most common locations include the lips, eyelids, face, tongue, oropharynx, extremities, and genitals, and in severe cases, it can compromise the upper airway, posing a risk of asphyxiation. The edema usually resolves within 72 hours without sequelae.