Algorithm of the approach to the diagnosis, treatment and monitoring of the patient with syphilis
Syphilis, VRDL, TPHA, Non-treponemal test, Treponemal test
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Algorithm: Syphilis: contact tracing
Algorithm that presents signs/symptoms that may raise the suspicion of the diagnosis of syphilis (primary, secondary, latent or tertiary) and defines criteria for the diagnosis based on the combination of the results of the treponemal test and non-treponemal test. It presents options for treatment and guidelines for monitoring/surveillance of therapeutic efficacy.
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Bibliography
- Janier M, Unemo M, Dupin N, Tiplica GS, Potocnik M, Patel R. 2020 European guideline on the management of Syphilis. JEADV. 2020.
- Cherneskie T, Bachmann L, Blan S, Bolan G, Daskalakis DC, Lee E, Neu N. The Diagnosis, Management and Prevention of Syphilis: An Update and Review. NYC Health and STD HIV Prevention Training Center. 2019.
- CDC- Centers for Disease Control and Prevention. Sexually Transmitted Diseases (STDs) – Syphilis. Disponível em https://www.cdc.gov/std/syphilis/default.htm
- Portal de Transparência do Serviço Nacional de Saúde. Doenças de declaração obrigatório – Sífilis – Excluindo Sífilis Congénita. Disponível em https://transparencia.sns.gov.pt
- Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny CA, Park I, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. US
- Department of Health and Human Services/Centers for Disease Control and Prevention – MMWR. 2021. 23;70(4):1-187.
- Rice M.D. et al. The Modern Epidemic of Syphilis N Engl J Med 2020; 382:845-854 DOI: 10.1056/NEJMra1901593